Post-Necrotic Scarring of the Liver in a Child and Its Possible Relationship to Rh Factor

a sequel of subacute massive hepatitis whether it arises in acute process or insidiously. Glynj1 and Himsworth (1944) and Glynn, Himsworth and Neuberger (1945) have demonstrated experimental rats that the dietetic deficiency sulphur containing amino-acid cystin resulted nj an acute massive hepatic necrosis after a latent period and the survivors of which developed post-necrotic scarring and nodular hyperplasiaIn human beings it most commonly arises spontaneously or in association with pregnancy toxsemia but may also arise during the therapeutic administration of certain organic chenrica substance, e.g. cinchophen, or may follow poison' ing by certain industrial chemicals, e.g. trinitrotoluene. So naturally the cause may be due to two factors, trophopathic and toxipathy Karsner (quoted by Lichtman, 1949) observed that post-necrotic scarring affects females more than males and although it may occur at any time of life, it is likely to affect younger age